Corticosteroids for endurance and pain killing

twistedneck · #1 (**permalink**) 09-14-2003, 01:26 AM

Can anyone shed some light on corticosteroids?

I am considering using topical and IM injectible corticosteroids (locoid cream 0.1% hydrocortizone butirate) and Kenacort (IM cortizone)..

Goal is pain reduction, euporic well being and released energy for endurance. These drugs are highly abused in the tour de france so they must work. Lance's mysterious saddle sore during the 02 tour caused him to use a banned cortico cream and he got popped but his doc signed off.. hmmm.

These drugs actually eat muscle/ bone/ and organ tissue for energy - they turn it into gylcogen! yummy. Long term abuse causes bone ends to break down and crumble. nice. Let me know bros.. i realize most bb wont touch this shit with a 10' pole.

TW

twistedneck · #2 (**permalink**) 09-14-2003, 04:53 PM

^

stackdizzy · #3 (**permalink**) 09-14-2003, 07:56 PM

I know there is one dude in my city that used depo medrol pretty extensivley in his powerlifting career for joint pain! I don't know anything about it other than the dudes body is so far fallen apart that he cannot lift weights anymore and he is in his late 30's I dunno if they caused it but it is something to consider! Anyways dude I know this sounds a but hypocritical but I personally would only take these under doctor supervision!! Good luck bro

kronah · #4 (**permalink**) 09-16-2003, 03:39 PM

I would not use them for an acute injury. They ultimately halt the healing process of the ligament or tendon. Not a good thing for bodybuilders by any means. If you need an anti-inflammatory take motrin 600-800mg 3 times a day for 15 days. I typed up some more detailed info on corticosteroids for those who are interested.

Corticosteroids belong to another class of drugs with anti-inflammatory properties. Derived from the hormone cortisol, corticosteroids are associated with much more pronounced and lasting anti-inflammatory effects compared with NSAIDs. Numerous studies have shown that they, in fact, can halt the healing process by virtually eliminating the inflammatory response. Inferior healing of ligament sprains and muscle strains has been observed in several animal models.For this reason, most healthcare professionals believe that corticosteroids have no role in the treatment of acute soft-tissue injuries.

Corticosteroids also remain a popular choice in the treatment of chronic soft-tissue injuries. Often they are used in a parenteral form and injected directly on and around the affected tendon. A corticosteroid injection can result in quick and dramatic relief of the pain symptoms associated with tendinopathy. The exact mechanism through which this is accomplished remains unclear, as inflammatory features are often absent in these lesions. Problems associated with corticosteroid use include weakening of the tendon and the possibility of tendon rupture.

skinny D · #5 (**permalink**) 09-16-2003, 04:47 PM

Quote:

Originally posted by kronah
If you need an anti-inflammatory take motrin 600-800mg 3 times a day for 15 days.

Use naprosyn (naproxen) 500mg 3times a day, I think aleave is almost the same thing. Work way better than motrin/t\

kronah · #6 (**permalink**) 09-16-2003, 05:09 PM

Naproxen is a little stronger anti-inflammatory but also is a little more harsher on the stomach. Both are good to use. If using naproxen definately take it with your meals or you may have some stomach upset.

twistedneck · #7 (**permalink**) 09-16-2003, 06:05 PM

Kronah, I appreciate your feedback. I didn't realize the main action was anti - inflamatory.

Q: Injectible cortizone (kenacort) causes euphoric pain relif and energy for long term endurance. Is this effect also seen with topical use?

kronah · #8 (**permalink**) 09-16-2003, 09:35 PM

Quote:

Originally posted by twistedneck
Q: Injectible cortizone (kenacort) causes euphoric pain relif and energy for long term endurance. Is this effect also seen with topical use?

Not to my knowledge. Topical preparations will only be minimally absorbed systemically in the body. Topical corticosteroids are mainly used for dermatologic conditions (posion ivy, heat rashes, etc) I think you would be wasting your time and money. Also if you are black, you run the risk of causing hypopigmintation of your skin (just a side not for any black BB considering using this)

twistedneck · #9 (**permalink**) 09-27-2003, 01:15 AM

I now have about 10 4mg tabs of methylprednisone (oral medrol). I plan on using them prior to long mountaing bike ride this weekend. Its 5hrs. Should I just take 8mg 1hr before or do i have to load up? Do i take during?

Can i apply topical hydrocoritzone buitrate and add a litte more?

skinny D · #10 (**permalink**) 09-27-2003, 01:45 AM

Rip them trails up bro/t\

twistedneck · #11 (**permalink**) 09-27-2003, 05:16 PM

Kronah, i got a study to back up what you said about not absorbing much through skin.

From RXmed on topical medrol (methylprednisolone)

Quote:

This effect is more commonly seen in patients with fair complexions or sensitive skin. Localized atrophy or striae have been reported with the use of topical corticosteroids particularly when used in the intertriginous areas. The remote possibility of systemic corticosteroid absorption does exist, particularly if extensive areas are treated or treatment is maintained for prolonged periods. It is estimated that 0.18 mg of methylprednisolone acetate would be absorbed daily if the contents of a 30 mL bottle were used over a period of 7 days.